Fabrication of Bacterial Cellulose-Curcumin Nanocomposite as a Novel Dressing for Partial Thickness Skin Burn.

ABSTRACT: The current study aimed to fabricate curcumin-loaded bacterial cellulose (BC-Cur) nanocomposite as a potential wound dressing for partial thickness burns by utilizing the therapeutic features of curcumin and unique structural, physico-chemical, and biological features of bacterial cellulose (BC). Characterization analyses confirmed the successful impregnation of curcumin into the BC matrix. Biocompatibility studies showed the better attachment and proliferation of fibroblast cells on the BC-Cur nanocomposite. The antibacterial potential of curcumin was tested against Escherichia coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), Salmonella typhimurium (S. typhimurium), and Staphylococcus aureus (S. aureus). Wound healing analysis

SUBMITTER: Sajjad W 

PROVIDER: S-EPMC7531241 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature