Constipation might be associated with risk of allergic rhinitis: A nationwide population-based cohort study.

ABSTRACT:

Background

Allergic rhinitis (AR) is a burdensome respiratory disorder whose etiology and pathophysiology remain controversial and most likely multifactorial. Accumulated evidence indicates that gut dysbiosis contributes to AR via the gut-airway axis. Constipation could result in alteration of the intestinal microflora. The clinical impact of constipation on AR has not been studied. We aimed to evaluate the risk of AR in constipated patients using a nationwide longitudinal population-based cohort.

Methods

We identified 57786 patients with constipation and 57786 matched controls between 1999 and 2013 from the Longitudinal Health Insurance Database, which is a subset of Taiwanese National Health Insurance Research Database. Propensity score analysis was used for matching age,

SUBMITTER: Wu MC 

PROVIDER: S-EPMC7531808 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature