Nutritional status, environmental enteric dysfunction, and prevalence of rotavirus diarrhoea among children in Zambia.

ABSTRACT:

Background

Rotavirus is the most common cause of fatal diarrhoeal disease among children under the age of five globally and is responsible for millions of hospitalizations each year. Although nutritional status and environmental enteric dysfunction (EED) are recognized as important predictors of susceptibility to diarrhoeal disease, no research to date has examined the mechanisms by which undernutrition and EED may protect against prevalence of rotavirus infection.

Methods

We utilized data collected from a study evaluating the effectiveness of Rotarix™ vaccine against severe gastroenteritis among children under the age of 5 in Zambia. The prevalence of malnutrition, wasting, and stunting at the time of study enrollment was calculated using WHO child growth standards. Commerc

SUBMITTER: Koyuncu A 

PROVIDER: S-EPMC7531814 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature