Generation of a malaria negative Ugandan birth weight standard for the diagnosis of small for gestational age.

ABSTRACT:

Objective

Placental malaria is a known risk factor for small for gestational age (SGA) neonates. However, currently utilized international and African birthweight standards have not controlled for placental malaria and/or lack obstetrical ultrasound dating. We developed a neonatal birthweight standard based on obstetrically dated pregnancies that excluded individuals with clinical malaria, asymptomatic parasitemia, and placental malaria infection. We hypothesized that current curves underestimate true ideal birthweight and the prevalence of SGA.

Study design

Participants were pooled from two double-blind randomized control trials of intermittent preventive therapy during pregnancy in Uganda. HIV-negative women without comorbidities were enrolled from 12-20 weeks gestation. G

SUBMITTER: Zakama AK 

PROVIDER: S-EPMC7531849 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature