Does prior mediastinal lymph node aspiration contribute to false-positive positron emission tomography-computed tomography?

ABSTRACT: Proper staging of the mediastinum is an essential component of lung cancer evaluation. Positron emission tomography-computed tomography (PETCT) and endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) are an integral part of this process. False-positive PETCT results can occur following surgical procedures but has not been demonstrated following EBUS-TBNA. We aimed to determine whether false-positive PETCT rates increase when EBUS-TBNA is performed prior to PETCT. A retrospective review was carried out of clinical cases that underwent both PETCT and EBUS-TBNA within 30 days for the suspected malignancy. The impact of test sequence on the PETCT false-positive rate (FPR) was determined using Generalised Estimating Equation logistic regression analysis. A total of 675 lymph n

SUBMITTER: Ramsahai JM 

PROVIDER: S-EPMC7533300 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature