Long Non-coding RNAs Are Differentially Expressed After Different Exercise Training Programs.

ABSTRACT:

Background

Molecular regulation related to the health benefits of different exercise modes remains unclear. Long non-coding RNAs (lncRNAs) have emerged as an RNA class with regulatory functions in health and diseases. Here, we analyzed the expression of lncRNAs after different exercise training programs and their possible modes of action related to physical exercise adaptations.

Methods

Public high-throughput RNA-seq data (skeletal muscle biopsies) were downloaded, and bioinformatics analysis was performed. We primarily analyzed data reports of 12 weeks of resistance training (RT), high-intensity interval training (HIIT), and combined (CT) exercise training. In addition, we analyzed data from 8 weeks of endurance training (ET). Differential expression analysis of lncRNAs was

SUBMITTER: Bonilauri B 

PROVIDER: S-EPMC7533564 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature