Risk for Arterial and Venous Thrombosis in Patients With Myeloproliferative Neoplasms: A Population-Based Cohort Study.

ABSTRACT: Background:Patients with myeloproliferative neoplasms (MPNs) are reported to be at increased risk for thrombotic events. However, no population-based study has estimated this excess risk compared with matched control participants. Objective:To assess risk for arterial and venous thrombosis in patients with MPNs compared with matched control participants. Design:Matched cohort study. Setting:Population-based setting in Sweden from 1987 to 2009, with follow-up to 2010. Patients:9429 patients with MPNs and 35 820 matched control participants. Measurements:The primary outcomes were rates of arterial and venous thrombosis. Flexible parametric models were used to calculate hazard ratios (HRs) and cumulative incidence with 95% CIs. Results:The HRs for arterial thrombosis among patients with MPNs

SUBMITTER: Hultcrantz M 

PROVIDER: S-EPMC7533681 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature