Estimation of Rift Valley fever virus spillover to humans during the Mayotte 2018-2019 epidemic.

ABSTRACT: Rift Valley fever (RVF) is an emerging, zoonotic, arboviral hemorrhagic fever threatening livestock and humans mainly in Africa. RVF is of global concern, having expanded its geographical range over the last decades. The impact of control measures on epidemic dynamics using empirical data has not been assessed. Here, we fitted a mathematical model to seroprevalence livestock and human RVF case data from the 2018-2019 epidemic in Mayotte to estimate viral transmission among livestock, and spillover from livestock to humans through both direct contact and vector-mediated routes. Model simulations were used to assess the impact of vaccination on reducing the epidemic size. The rate of spillover by direct contact was about twice as high as vector transmission. Assuming 30% of the population we

SUBMITTER: Metras R 

PROVIDER: S-EPMC7533885 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature