Vitamin B6, vitamin B12 and methionine and risk of pancreatic cancer: a meta-analysis.

ABSTRACT:

Background

Nutrients involved in one-carbon metabolism may play a key role in pancreatic carcinogenesis. The aim of this study was to examine the association between pancreatic cancer risk and intake or blood levels of vitamins B6, B12 and methionine via meta-analysis.

Methods

A systematic search was performed in PubMed, Web of Knowledge and Chinese National Knowledge Infrastructure (CNKI) up to April 2020 to identify relevant studies. Risk estimates and their 95% confidence intervals (CIs) were retrieved from the studies and combined by a random-effect model.

Results

A total of 18 studies were included in this meta-analysis on the association of vitamin B6, B12 and methionine with pancreatic cancer risk. The combined risk estimate (95% CI) of pancreatic cancer for th

SUBMITTER: Wei DH 

PROVIDER: S-EPMC7534168 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature