A comparison of treatment and outcomes of perihilar cholangiocarcinoma between Eastern and Western centers.

ABSTRACT:

Background

Perihilar cholangiocarcinoma (PHC) often requires extensive surgery which is associated with substantial morbidity and mortality. This study aimed to compare an Eastern and Western PHC cohort in terms of patient characteristics, treatment strategies and outcomes including a propensity score matched analysis.

Methods

All consecutive patients who underwent combined biliary and liver resection for PHC between 2005 and 2016 at two Western and one Eastern center were included. The overall perioperative and long-term outcomes of the cohorts were compared and a propensity score matched analysis was performed to compare perioperative outcomes.

Results

A total of 210 Western patients were compared to 164 Eastern patients. Western patients had inferior survival compa

SUBMITTER: Olthof PB 

PROVIDER: S-EPMC7534176 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature