Crystal structure of 6-azido-6-de-oxy-1,2-O-iso-propyl-idene-α-d-gluco-furan-ose.

ABSTRACT: Short syntheses to high Fsp ³ index natural-product analogues such as imino-sugars are of paramount importance in the investigation of their biological activities and reducing the use of protecting groups is an advantageous synthetic strategy. An iso-propyl-idene group was employed towards the synthesis of seven-membered ring imino-sugars and the title compound, C₉H₁₅N₃O₅, was crystallized as an inter-mediate, in which the THF ring is twisted and the dioxolane ring adopts an envelope conformation: the dihedral angle between the rings is 67.50 (13)°. In the crystal, the hydroxyl groups participate in O-H⋯(O,O) and O-H⋯N hydrogen-bonding inter-actions, which generate chains of mol-ecules propagating parallel to the a-axis d

SUBMITTER: Wood A 

PROVIDER: S-EPMC7534240 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature