Locating the Sex Determining Region of Linkage Group 12 of Guppy (Poecilia reticulata).

ABSTRACT: Despite over 100 years of study, the location of the fully sex-linked region of the guppy (Poecilia reticulata) carrying the male-determining locus, and the regions where the XY pair recombine, remain unclear. Previous population genomics studies to determine these regions used small samples from recently bottlenecked captive populations, which increase the false positive rate of associations between individuals' sexes and SNPs. Using new data from multiple natural populations, we show that a recently proposed candidate for this species' male-determining gene is probably not completely sex-linked, leaving the maleness factor still unidentified. Variants in the chromosome 12 region carrying the candidate gene sometimes show linkage disequilibrium with the sex-determining factor, but

SUBMITTER: Charlesworth D 

PROVIDER: S-EPMC7534449 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature