A Nested Association Mapping Panel in Arabidopsis thaliana for Mapping and Characterizing Genetic Architecture.
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ABSTRACT: Linkage and association mapping populations are crucial public resources that facilitate the characterization of trait genetic architecture in natural and agricultural systems. We define a large nested association mapping panel (NAM) from 14 publicly available recombinant inbred line populations (RILs) of Arabidopsis thaliana, which share a common recurrent parent (Col-0). Using a genotype-by-sequencing approach (GBS), we identified single nucleotide polymorphisms (SNPs; range 563-1525 per population) and subsequently built updated linkage maps in each of the 14 RIL sets. Simulations in individual RIL populations indicate that our GBS markers have improved power to detect small effect QTL and enhanced resolution of QTL support intervals in comparison to original linkage maps. Using
SUBMITTER: Brock MT
PROVIDER: S-EPMC7534452 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
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