Prolonged nucleic acid conversion and false-negative RT-PCR results in patients with COVID-19: A case series.

ABSTRACT:

Background

Prolonged nucleic acid conversion and false-negative real-time polymerase chain reaction (RT-PCR) results might occur in COVID-19 patients rather than infection recurrence.

Presentation of cases

We reported four cases who had negative RT-PCR results, in addition to the last two consecutive negative results. Patient-1 had negative RT-PCR results twice (the 6th and 8th) from a total of 11 swabs. Patient-2 had negative RT-PCR results once (the 5th) from a total of 8 swabs. Patient-3 showed negative results of RT-PCR twice (the 4th and 6th) from a total of 11 swabs. Patient-4 had negative RT-PCR results twice (the 2nd and 10th) from a total of 14 swabs.

Discussion

The fluctuating trend of our RT-PCR results in our cases might be due to insufficient viral materi

SUBMITTER: Trisnawati I 

PROVIDER: S-EPMC7536520 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature