Trends in Optic Neuritis Incidence and Prevalence in the UK and Association With Systemic and Neurologic Disease.

ABSTRACT:

Importance

Epidemiologic data on optic neuritis (ON) incidence and associations with immune-mediated inflammatory diseases (IMIDs) are sparse.

Objective

To estimate 22-year trends in ON prevalence and incidence and association with IMIDs in the United Kingdom.

Design, setting, and participants

This cohort study analyzed data from The Health Improvement Network from January 1, 1995, to September 1, 2019. The study included 10 937 511 patients 1 year or older with 75.2 million person-years' follow-up. Annual ON incidence rates were estimated yearly (January 1, 1997, to December 31, 2018), and annual ON prevalence was estimated by performing sequential cross-sectional studies on data collected on January 1 each year for the same period. Data for 1995, 1996, and 2019 were

SUBMITTER: Braithwaite T 

PROVIDER: S-EPMC7536630 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature