The Histological Picture of Indication Biopsies in the First 2 Weeks after Kidney Transplantation.

ABSTRACT:

Background and objectives

In preclinical studies, ischemia-reperfusion injury and older donor age are associated with graft inflammation in the early phase after transplantation. In human kidney transplantation, impaired allograft function in the first days after transplantation is often adjudicated to donor- and procedure-related characteristics, such as donor age, donor type, and ischemia times.

Design

, setting, participants, & measurementsIn a cohort of 984 kidney recipients, 329 indication biopsies were performed within the first 14 days after transplantation. The histologic picture of these biopsies and its relationship with alloimmune risk factors and donor- and procedure-related characteristics were studied, as well as the association with graft failure. Multi

SUBMITTER: Van Loon E 

PROVIDER: S-EPMC7536761 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature