Performance of the Kidney Failure Risk Equation by Disease Etiology in Advanced CKD.

ABSTRACT:

Background and objectives

The kidney failure risk equation is a clinical tool commonly used for prediction of progression from CKD to kidney failure. The kidney failure risk equation's accuracy in advanced CKD and whether this varies by CKD etiology remains unknown. This study examined the kidney failure risk equation's discrimination and calibration at 2 and 5 years among a large tertiary care population with advanced CKD from heterogeneous etiologies.

Design, setting, participants, & measurements

This retrospective cohort study included 1293 patients with advanced CKD (median eGFR 15 ml/min per 1.73 m²) referred to the Ottawa Hospital Multi-Care Kidney Clinic between 2010 and 2016, with follow-up clinical data available through 2018. Four-variable kidney failure

SUBMITTER: Hundemer GL 

PROVIDER: S-EPMC7536763 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature