Preconception Perceived Stress Is Associated with Reproductive Hormone Levels and Longer Time to Pregnancy.

ABSTRACT: BACKGROUND:Women who experience pregnancy loss are especially prone to high stress, though the effects of stress on reproductive outcomes in this vulnerable population are unknown. We assessed relationships between perceived stress and hormones, anovulation, and fecundability among women with prior loss. METHODS:One thousand two hundred fourteen women with 1-2 prior losses were followed for ≤6 cycles while attempting pregnancy and completed end-of-cycle stress assessments. For cycles 1 and 2, women also collected daily urine and completed daily perceived stress assessments. We assessed anovulation via. an algorithm based on human chorionic gonadotropin (hCG), pregnanediol-3-glucuronide (PdG), luteinizing hormone (LH), and fertility monitor readings. Pregnancy was determined via. hCG. Adjus

SUBMITTER: Schliep KC 

PROVIDER: S-EPMC7536839 | biostudies-literature | 2019 Nov

REPOSITORIES: biostudies-literature