Muscle involvement in SARS-CoV-2 infection.

ABSTRACT:

Background and purpose

Since the outbreak of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic, several reports indicated neurological involvement in COVID-19 disease. Muscle involvement has also been reported as evidenced by creatine kinase (CK) elevations and reports of myalgia.

Methods

Creatine kinase, markers of inflammation, pre-existing diseases and statin use were extracted from records of Austrian hospitalised COVID-19 patients. Disease severity was classified as severe in case of intensive care unit (ICU) admission or mortality. COVID-19 patients were additionally compared to an historical group of hospitalised influenza patients.

Results

Three hundred fifty-one patients with SARS-CoV-2 and 258 with influenza were included in the final

SUBMITTER: Pitscheider L 

PROVIDER: S-EPMC7537196 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature