5-HT₃ receptor antagonists for the prevention of perioperative shivering undergoing spinal anaesthesia: a systematic review and meta-analysis of randomised controlled trials.

ABSTRACT:

Objective

Perioperative shivering (POS) is a common complication in patients undergoing spinal anaesthesia. The present study investigated the efficacy of 5-HT₃ receptor antagonists in preventing POS following spinal anaesthesia.

Design

Systematic review and meta-analysis.

Data sources

Pubmed, Embase, the Web of Science and Cochrane Library were searched from database establishment on 31 July 2019.

Eligibility criteria

Randomised controlled trials that reported the effects of 5-HT₃ receptor antagonists in the prevention of POS in patients after spinal anaesthesia.

Data extraction and synthesis

Two reviewers independently extracted data. The primary outcome of the present study was the incidence of POS. The risk of bias for the inclu

SUBMITTER: Shen QH 

PROVIDER: S-EPMC7537433 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature