Clinical Predictors of Influenza in Young Children: The Limitations of "Influenza-Like Illness".

ABSTRACT:

Background

Influenza-like illness (ILI) definitions have been infrequently studied in young children. Despite this, clinical definitions of ILI play an important role in influenza surveillance. This study aims to identify clinical predictors of influenza infection in children ≤5 years old from which age-specific ILI definitions are then constructed.

Methods

Children aged 6-59 months with a history of fever and acute respiratory symptoms were recruited in the Western Australia Influenza Vaccine Effectiveness (WAIVE) Study. Clinical data and per-nasal specimens were obtained from all children. Logistic regression identified significant predictors of influenza infection. Different ILI definitions were compared for diagnostic accuracy.

Results

Children were recruited from

SUBMITTER: Conway NT 

PROVIDER: S-EPMC7537662 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature