Clinical characteristics and risk factors of liver injury in COVID-19: a retrospective cohort study from Wuhan, China.

ABSTRACT:

Background

Coronavirus disease 2019 (COVID-19) has rapidly become a major international public health concern. This study was designed to evaluate the clinical characteristics and risk factors of COVID-19-associated liver injury.

Methods

A fraction of 657 COVID-19 patients were retrospectively analyzed. Clinical and laboratory data were derived from electronic medical records and compared between patients with or without liver injury. Multivariate logistic regression method was used to analyze the risk factors for liver injury.

Results

Among 657 patients, 303 (46.1%) patients had liver injury with higher rate in severe/critically ill patients [148/257 (57.6%)] than those in moderate cases [155/400 (38.8%)]. The incidence of liver injury was much higher in male [192/30

SUBMITTER: Wang M 

PROVIDER: S-EPMC7539280 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature