Extracellular volume fraction measurement correlates with lymphocyte abundance in thymic epithelial tumors.

ABSTRACT:

Background

Recent advance in tissue characterization with parametric mapping imaging has the potential to be a novel biomarker for histopathologic correlation with thymic epithelial tumors (TETs). The purpose of our study is to evaluate MRI T1 mapping with the calculation of extracellular volume (ECV) fraction for histologic correlation with thymic epithelial tumor based on lymphocyte abundance.

Methods

A retrospective study including 31 consecutive patients (14 men and 17 women, median age, 56 years; interquartile range, 12 years) with TETs was performed. The T1 values and ECV were assessed by using quantitative MRI mapping techniques. Mann-Whitney U test, Kruskal-Wallis H test, and receiver operating characteristic curve analyses were used to assess discrimination between

SUBMITTER: Chang CC 

PROVIDER: S-EPMC7539449 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature