PRIME-HF: Novel Exercise for Older Patients with Heart Failure. A Pilot Randomized Controlled Study.

ABSTRACT:

Objectives

To test the hypothesis that (1) older patients with heart failure (HF) can tolerate COMBined moderate-intensity aerobic and resistance training (COMBO), and (2) 4 weeks of Peripheral Remodeling through Intermittent Muscular Exercise (PRIME) before 4 weeks of COMBO will improve aerobic capacity and muscle strength to a greater extent than 8 weeks of COMBO.

Design

Prospective randomized parallel open-label blinded end point.

Setting

Single-site Australian metropolitan hospital.

Participants

Nineteen adults (72.8 ± 8.4 years of age) with heart failure with reduced ejection fraction (HFrEF).

Intervention

Participants were randomized to 4 weeks of PRIME or COMBO (phase 1). All participants subsequently completed 4 weeks of COMBO (phase 2). Sessions

SUBMITTER: Giuliano C 

PROVIDER: S-EPMC7540058 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature