Neurological symptom burden impacts survival prognosis in patients with newly diagnosed non-small cell lung cancer brain metastases.

ABSTRACT:

Background

Brain metastases (BM) are a frequent complication of advanced cancer and are characterized by a variety of neurological symptoms. Although the presence of neurological symptoms is included in the response assessment in patients with primary brain tumors, to the authors' knowledge little is known regarding the prognostic impact of neurological symptoms in patients with BM.

Methods

Patients with newly diagnosed BM from non-small cell lung cancer were identified from the Vienna Brain Metastasis Registry and were evaluated according to the incidence, distribution, and prognostic impact of neurological symptoms at the time of diagnosis of BM.

Results

A total of 1608 patients (57.3% male and 42.7% female; median age, 62 years) were available for further analyses.

SUBMITTER: Steindl A 

PROVIDER: S-EPMC7540353 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature