Using online tools at the Bovine Genome Database to manually annotate genes in the new reference genome.

ABSTRACT: With the availability of a new highly contiguous Bos taurus reference genome assembly (ARS-UCD1.2), it is the opportune time to upgrade the bovine gene set by seeking input from researchers. Furthermore, advances in graphical genome annotation tools now make it possible for researchers to leverage sequence data generated with the latest technologies to collaboratively curate genes. For many years the Bovine Genome Database (BGD) has provided tools such as the Apollo genome annotation editor to support manual bovine gene curation. The goal of this paper is to explain the reasoning behind the decisions made in the manual gene curation process while providing examples using the existing BGD tools. We will describe the sources of gene annotation evidence provided at the BGD, including RNA-seq

SUBMITTER: Triant DA 

PROVIDER: S-EPMC7540445 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature