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ABSTRACT: Purpose
To present and validate a method for automated extraction and analysis of the temporal evolution of the mitral valve (MV) vortex ring from MR 4D-flow data.Methods
The proposed algorithm uses the divergence-free part of the velocity vector field for Q criterion-based identification and tracking of MV vortex ring core and region within the left ventricle (LV). The 4D-flow data of 20 subjects (10 healthy controls, 10 patients with ischemic heart disease) were used to validate the algorithm against visual analysis as well as to assess the method's sensitivity to manual LV segmentation. Quantitative MV vortex ring parameters were analyzed with respect to both their differences between healthy subjects and patients and their correlation with transmitral peak velocities.
SUBMITTER: Krauter C
PROVIDER: S-EPMC7540523 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature