Structural Elucidation of the Mechanism of Molecular Recognition in Chiral Crystalline Sponges.

ABSTRACT: To gain insight into chiral recognition in porous materials we have prepared a family of fourth generation chiral metal-organic frameworks (MOFs) that have rigid frameworks and adaptable (flexible) pores. The previously reported parent material, [Co₂ (S-mandelate)₂ (4,4'-bipyridine)₃ ](NO₃ )₂ , CMOM-1S, is a modular MOF; five new variants in which counterions (BF₄^- , CMOM-2S) or mandelate ligands are substituted (2-Cl, CMOM-11R; 3-Cl, CMOM-21R; 4-Cl, CMOM-31R; 4-CH₃ , CMOM-41R) and the existing CF₃ SO₃^- variant CMOM-3S are studied herein. Fine-tuning of pore size, shape, and chemistry afforded a series of distinct host-guest binding sites with variable chiral separation

SUBMITTER: Zhang SY 

PROVIDER: S-EPMC7540565 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature