Nonalcoholic fatty liver disease burden: Australia, 2019-2030.

ABSTRACT: BACKGROUND AND AIM:Nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) account for a large and growing proportion of liver disease burden globally. The burden of NAFLD/NASH manifests in increasing levels of advanced liver disease and primary liver cancer in Australia. A Markov model was used to forecast NAFLD burden in Australia through 2030. METHODS:A model was used to estimate fibrosis progression, primary liver cancer, and liver deaths among the Australian NAFLD population, with changes in incident NAFLD cases based on long-term trends for changes in the prevalence of obesity. Published estimates and surveillance data were applied to build and validate the model projections, including surveillance data for the incidence of liver cancer. RESULTS:Prevalent NAF

SUBMITTER: Adams LA 

PROVIDER: S-EPMC7540570 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature