Evidence for inhibited temperament as a transdiagnostic factor across mood and psychotic disorders.

ABSTRACT:

Background

The conceptualization of risk for psychiatric illness is moving from risk factors for specific psychiatric disorders to factors that confer risk for multiple disorders. One potential transdiagnostic risk factor is inhibited temperament, a trait characterized by a fearful or avoidant response to novelty. Inhibited temperament is an established risk factor for anxiety disorders, and evidence suggests inhibited temperament is elevated in schizophrenia, bipolar disorder, and major depressive disorder.

Methods

In the current study, we tested the hypothesis that inhibited temperament is a transdiagnostic factor in 490 participants including individuals with schizophrenia (n=184), psychotic bipolar disorder (n=61), major depression disorder (n=53), or no disorders (n=192

SUBMITTER: Feola B 

PROVIDER: S-EPMC7540608 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature