Nanofibrous cosmetic face mask for transdermal delivery of nano gold: synthesis, characterization, release and zebra fish employed toxicity studies.

ABSTRACT: This study involves the generation of gold nanoparticles (Au NPs) via a novel natural/non-toxic methodology using tea and orange-peel extracts. These were then embedded into a novel blend composed of a polyethylene oxide and gelatin (PEO-Gel) fibre mat. The scanning electron microscopy results indicated that the addition of both collagen (COL) and ascorbic acid (AA) into the PEO-Gel system (PEO-Gel-AA-COL system) enhances the Au NP incorporation into nanofibres leading to a diameter of 164.60 ± 20.95 and 192.43 ± 39.14 nm in contrast to the spraying observed with the Au PEO-Gel system alone. Releasing studies conducted over 30 min indicated that the PEO-Gel-AA-COL-orange peel Au (OpAu) system accounts for a higher content of Au release than the green tea Au (GtAu) NP system where a maximum

SUBMITTER: Manatunga DC 

PROVIDER: S-EPMC7540761 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature