Transcriptome analysis identified long non-coding RNAs involved in the adaption of yak to high-altitude environments.

ABSTRACT: The mechanisms underlying yak adaptation to high-altitude environments have been investigated using various methods, but no report has focused on long non-coding RNA (lncRNA). In the present study, lncRNAs were screened from the gluteus transcriptomes of yak and their transcriptional levels were compared with those in Sanjiang cattle, Holstein cattle and Tibetan cattle. The potential target genes of the differentially expressed lncRNAs between species/strains were predicted using cis and trans models. Based on cis-regulated target genes, no KEGG pathway was significantly enriched. Based on trans-regulated target genes, 11 KEGG pathways in relation to energy metabolism and three KEGG pathways associated with muscle contraction were significantly enriched. Compare

SUBMITTER: Xin JW 

PROVIDER: S-EPMC7540768 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature