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Healthy cardiovascular biomarkers across the lifespan in wild-born chimpanzees (Pan troglodytes).


ABSTRACT: Chimpanzees (Pan troglodytes) are a crucial model for understanding the evolution of human health and longevity. Cardiovascular disease is a major source of mortality during ageing in humans and therefore a key issue for comparative research. Current data indicate that compared to humans, chimpanzees have proatherogenic blood lipid profiles, an important risk factor for cardiovascular disease in humans. However, most work to date on chimpanzee lipids come from laboratory-living populations where lifestyles diverge from a wild context. Here, we examined cardiovascular profiles in chimpanzees living in African sanctuaries, who range semi-free in large forested enclosures, consume a naturalistic diet, and generally experience conditions more similar to a wild chimpanzee lifestyle. We m

SUBMITTER: Cole MF 

PROVIDER: S-EPMC7540951 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature