Community-level impacts of spatial repellents for control of diseases vectored by Aedes aegypti mosquitoes.

ABSTRACT: Spatial repellents (SRs) reduce human-mosquito contact by preventing mosquito entrance into human-occupied spaces and interfering with host-seeking and blood-feeding. A new model to synthesize experimental data on the effects of transfluthrin on Aedes aegypti explores how SR effects interact to impact the epidemiology of diseases vectored by these mosquitoes. Our results indicate that the greatest impact on force of infection is expected to derive from the chemical's lethal effect but delayed biting and the negative effect this may have on the mosquito population could elicit substantial impact in the absence of lethality. The relative contributions of these effects depend on coverage, chemical dose, and housing density. We also demonstrate that, through an increase in the number of potent

SUBMITTER: Ten Bosch QA 

PROVIDER: S-EPMC7541056 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature