Rates of primary and secondary treatments for patients on active surveillance for localized prostate cancer-A population-based cohort study.

ABSTRACT:

Background

The rate of primary and secondary treatment while on active surveillance (AS) for localized prostate cancer at the general population level is unknown. Our objective was to determine the patterns of secondary treatments after primary surgery or radiation for patients who undergo AS.

Methods

This was a population-based retrospective cohort study of men aged 50-80 years old in Ontario, Canada, between 2008 and 2016. We identified 26 742 patients with prostate cancer, a Gleason grade score ≤7, and an index prostate-specific antigen ≤10 ng/mL. Patients were categorized as undergoing AS with or without delayed primary treatment (DT; treatment >6 months after diagnosis) versus immediate treatment (IT; treatment ≤6 months). Patients receiving DT and IT were propensity sc

SUBMITTER: Matta R 

PROVIDER: S-EPMC7541139 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature