Fabrication of monodispersed copper oxide nanoparticles with potential application as antimicrobial agents.

ABSTRACT: Cuprous oxide nanoparticles (Cu₂O NPs) were fabricated in reverse micellar templates by using lipopeptidal biosurfactant as a stabilizing agent. Scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive x-ray spectrum (EDX) and UV-Vis analysis were carried out to investigate the morphology, size, composition and stability of the nanoparticles synthesized. The antibacterial activity of the as-synthesized Cu₂O NPs was evaluated against Gram-positive B. subtilis CN2 and Gram-negative P. aeruginosa CB1 strains, based on cell viability, zone of inhibition and minimal inhibitory concentration (MIC) indices. The lipopeptide stabilized Cu₂O NPs with an ultra-small size of 30 ± 2 nm diameter exhibited potent antimicrobial activity

SUBMITTER: Bezza FA 

PROVIDER: S-EPMC7541485 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature