Fine Particulate Matter Air Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients.

ABSTRACT:

Background

Air pollution is a carcinogen and causes pulmonary and cardiac complications. We examined the association of fine particulate matter pollution (PM_2.5) and mortality from cancer and all causes among pediatric, adolescent, and young adult (AYA) patients with cancer in Utah, a state with considerable variation in PM_2.5.

Methods

We followed 2,444 pediatric (diagnosed ages 0-14) and 13,459 AYA (diagnosed ages 15-39) patients diagnosed in 1986-2015 from diagnosis to 5 and 10 years postdiagnosis, death, or emigration. We measured average monthly PM_2.5 by ZIP code during follow-up. Separate pediatric and AYA multivariable Cox models estimated the association of PM_2.5 and mortality. Among AYAs, we examined effect modification of

SUBMITTER: Ou JY 

PROVIDER: S-EPMC7541555 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature