Do Histopathology and Clinical Outcomes of Breast Atypia Vary by Race/Ethnicity?

ABSTRACT:

Background

The clinical behavior of breast cancer varies by racial and ethnic makeup (REM), but the impact of REM on the clinical outcomes of breast atypia remains understudied. We examined the impact of REM on risk of underlying or subsequent carcinoma following a diagnosis of breast atypia.

Methods

In this retrospective, single-institution chart review, adult women diagnosed with breast atypia (atypical ductal hyperplasia, atypical lobular hyperplasia, or lobular carcinoma in situ) were stratified by REM. Regression modeling was used to estimate risk of underlying or subsequent carcinoma.

Results

We identified 539 patients with breast atypia, including 15 Hispanic (2.8%), 127 non-Hispanic black (23.6%), and 397 non-Hispanic white women (73.7%). Diagnoses included 75

SUBMITTER: Sergesketter AR 

PROVIDER: S-EPMC7541625 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature