Racial/Ethnic Differences in Ovarian Cancer Risk: Results from the Multiethnic Cohort Study.

ABSTRACT:

Background

Incidence rates of epithelial ovarian cancer (EOC) vary across racial/ethnic groups, yet little is known about the impact of hormone-related EOC risk factors in non-Whites.

Methods

Among 91,625 female Multiethnic Cohort Study participants, 155 incident EOC cases were diagnosed in Whites, 93 in African Americans, 57 in Native Hawaiians, 161 in Japanese Americans, and 141 in Latinas. We used Cox proportional hazards regression models to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations between race/ethnicity and EOC risk and between hormone-related factors and EOC risk across racial/ethnic groups.

Results

Compared with Whites, African Americans and Japanese Americans had a lower multivariable-adjusted EOC risk; Native Hawaiians ha

SUBMITTER: Sarink D 

PROVIDER: S-EPMC7541726 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature