Epidemiologic and Health Economic Evaluation of Cervical Cancer Screening in Rural China.

ABSTRACT:

Background

Cervical cancer is preventable and curable by detected early and managed effectively. To explore the most economical and effective cervical cancer screening strategies would lay a solid foundation for reducing the health and economic burden of cervical cancer.

Methods

A Markov model was established for a cohort of 100,000 female to simulate the natural history of cervical cancer. 18 screening strategies were estimated including careHPV, Thin prep cytologic (TCT), Visual inspection with acetic acid/ Lugol's iodine (VIA / VILI), careHPV in series with VIA / VILI, careHPV in series with TCT, three methods parallel connection every 1, 3, 5 years respectively. Model outcomes included cumulative risk of incidence and death of cervical cancer, quality-adjusted life years

SUBMITTER: Zhao F 

PROVIDER: S-EPMC7541874 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature