The impact of endometrial injury on reproductive outcomes: results of an updated meta-analysis.

ABSTRACT:

Background

It is still unclear whether endometrial injury (EI) has a beneficial effect on reproductive outcomes, and if so, the optimal procedure characteristics are not clear. All previous papers concluded that more research is needed, and as additional studies were recently published, the insights on EI have changed significantly.

Methods

Searches were conducted in MEDLINE, Embase, Web of Science, and Cochrane Library, to identify randomized controlled trials examining the EI effect on IVF outcomes in women at least one previous failed cycle.

Results

2015 references were identified through database searching. Ultimately, 17 studies were included, involving 3016 patients. Clinical pregnancy rate (CPR) (RR = 1.19, [95% CI 1.06-1.32], P = .003) and live birth ra

SUBMITTER: Nahshon C 

PROVIDER: S-EPMC7542009 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature