Copper-azide nanoparticle: a 'catalyst-cum-reagent' for the designing of 5-alkynyl 1,4-disubstituted triazoles.

ABSTRACT: A single pot, wet chemical route has been applied for the synthesis of polymer supported copper azide, CuN₃, nanoparticles (CANP). The hybrid system was used as 'catalyst-cum-reagent' for the azide-alkyne cyclo-addition reaction to construct triazole molecules using substituted benzyl bromide and terminal alkyne. The electron donating group containing terminal alkyne produced 5-alkynyl 1,4-disubstituded triazole product whereas for alkyne molecule with terminal electron withdrawing group facilitate the formation of 1,4-disubstituted triazole molecule.

SUBMITTER: Nandi D 

PROVIDER: S-EPMC7542177 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature