Genomic analyses reveal evolutionary and geologic context for the plateau fungus Ophiocordyceps sinensis.

ABSTRACT:

Background

Ophiocordyceps sinensis, which is only naturally found in the high-elevation extreme environment of the Tibetan Plateau, has been used in traditional Chinese medicine. Information concerning the evolutionary and geologic context of O. sinensis remains limited, however.

Methods

We constructed the high-quality genome of O. sinensis and provided insight into the evolution and ecology of O. sinensis using comparative genomics.

Results

We mapped the whole genome of the anamorph/asexual form Hirsutella of O. sinensis using Illumina and PacBio sequencing technologies and obtained a well assembled genome of 119.2 Mbp size. Long-read Single Molecule Real Time (SMRT) sequencing technology generated an assembly with more accur

SUBMITTER: Liu J 

PROVIDER: S-EPMC7542391 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature