Determinants of health-related quality of life decline in interstitial lung disease.

ABSTRACT:

Background

Health-related quality of life (HRQL) in interstitial lung disease (ILD) patients is impaired. We aimed to identify baseline predictors for HRQL decline within a 12-month observation period.

Methods

We analyzed 194 ILD patients from two German ILD-centers in the observational HILDA study. We employed the disease-specific King's Brief Interstitial Lung Disease questionnaire (K-BILD) with the subdomains 'psychological impact', 'chest symptoms' and 'breathlessness and activities', and the generic EQ-5D Visual Analog Scale (VAS). We evaluated how many patients experienced a clinically meaningful decline in HRQL. Subsequently, we investigated medical and sociodemographic factors as potential predictors of HRQL deterioration.

Results

Within the study population (

SUBMITTER: Maqhuzu PN 

PROVIDER: S-EPMC7542726 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature