Exercise in older women with breast cancer during systemic therapy: study protocol of a randomised controlled trial (BREACE).

ABSTRACT:

Introduction

Exercise interventions have been widely investigated in patients with cancer and demonstrate beneficial effects. However, intervention studies that include older women with breast cancer exercising during medical treatment are scarce. Hence, the aim of this study is to investigate the effect of a 12-week exercise-based intervention in older women (≥65 years) with breast cancer receiving (neo)adjuvant or first-line or second-line systemic therapy.

Methods and analysis

This is a single-centre, two-armed randomised controlled trial. We anticipate including 100 patients, who will be randomised 1:1 to exercise-based intervention or control stratified by treatment setting ((neo)adjuvant or metastatic) and treatment (chemotherapy or endocrine therapy + cyclin-dependent

SUBMITTER: Andersen HH 

PROVIDER: S-EPMC7542931 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature