Association between omentin-1 and major cardiovascular events after lower extremity endovascular revascularization in diabetic patients: a prospective cohort study.

ABSTRACT:

Background

Cardiovascular complications represent the major cause of morbidity and mortality of type 2 diabetes mellitus (T2DM) patients. In particular, peripheral artery disease (PAD) represents a frequent T2DM vascular complication and a risk factor for the development of major adverse cardiovascular events (MACE). Among adipokines, omentin-1 serum levels are reduced in T2DM patients with PAD and are inversely related to disease severity.

Objective

To study the relationship between omentin-1 levels, at baseline, with outcomes after endovascular procedures in T2DM patients with PAD and chronic limb-threatening ischemia (CLTI).

Research design and methods

We enrolled for our prospective non-randomized study, 207 T2DM patients with PAD and CLTI, requiring revasculariza

SUBMITTER: Biscetti F 

PROVIDER: S-EPMC7542958 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature