Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults.

ABSTRACT:

Background

Frailty, increased vulnerability to physiological stressors, is associated with adverse outcomes. COVID-19 exhibits a more severe disease course in older, comorbid adults. Awareness of atypical presentations is critical to facilitate early identification.

Objective

To assess how frailty affects presenting COVID-19 symptoms in older adults.

Design

Observational cohort study of hospitalised older patients and self-report data for community-based older adults.

Setting

Admissions to St Thomas' Hospital, London with laboratory-confirmed COVID-19. Community-based data for older adults using the COVID Symptom Study mobile application.

Subjects

Hospital cohort: patients aged 65 and over (n = 322); unscheduled hospital admission between 1 March 2020 an

SUBMITTER: Zazzara MB 

PROVIDER: S-EPMC7543251 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature