A Distinct Phylogenetic Cluster of Indian Severe Acute Respiratory Syndrome Coronavirus 2 Isolates.

ABSTRACT:

Background

From an isolated epidemic, coronavirus disease 2019 has now emerged as a global pandemic. The availability of genomes in the public domain after the epidemic provides a unique opportunity to understand the evolution and spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus across the globe.

Methods

We performed whole-genome sequencing of 303 Indian isolates, and we analyzed them in the context of publicly available data from India.

Results

We describe a distinct phylogenetic cluster (Clade I/A3i) of SARS-CoV-2 genomes from India, which encompasses 22% of all genomes deposited in the public domain from India. Globally, approximately 2% of genomes, which to date could not be mapped to any distinct known cluster, fall within this clade.<

SUBMITTER: Banu S 

PROVIDER: S-EPMC7543508 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature