In-hospital mortality is associated with inflammatory response in NAFLD patients admitted for COVID-19.

ABSTRACT:

Background & aims

Although metabolic risk factors are associated with more severe COVID-19, there is little evidence on outcomes in patients with non-alcoholic fatty liver disease (NAFLD). We here describe the clinical characteristics and outcomes of NAFLD patients in a cohort hospitalised for COVID-19.

Methods

This study included all consecutive patients admitted for COVID-19 between February and April 2020 at Imperial College Healthcare NHS Trust, with either imaging of the liver available dated within one year from the admission or a known diagnosis of NAFLD. Clinical data and early weaning score (EWS) were recorded. NAFLD diagnosis was based on imaging or past medical history and patients were stratified for Fibrosis-4 (FIB-4) index. Clinical endpoints were admission to

SUBMITTER: Forlano R 

PROVIDER: S-EPMC7544083 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature