Unfractionated Heparin in SARS-CoV-2 Pneumonia: Ischemic Stroke Case Report.

ABSTRACT: Thromboembolism is a known phenomenon in patients with Coronavirus disease 2019 (COVID-19). Recent investigations have revealed that a significant proportion of those hospitalized with severe COVID-19 demonstrate clinical and laboratory markers compatible with hypercoagulability, which is differentiated from disseminated intravascular coagulation (DIC), termed COVID-associated coagulopathy. Additionally, there is increasing concern for development of acute ischemic stroke because of this hypercoagulable state. We present a patient with COVID-19 pneumonia who was managed with unfractionated heparin (UFH) infusion and developed a large ischemic infarct shortly after cessation of the infusion. In retrospect, the patient's coagulation parameters were consistent with overt DIC, although some of

SUBMITTER: Efendizade A 

PROVIDER: S-EPMC7545009 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature